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Cancer incidence, patterns, and genotype–phenotype associations in individuals with pathogenic or likely pathogenic germline TP53 variants: an observational cohort study

Kelvin César de Andrade, Payal P Khincha, Jessica N Hatton, Megan N Frone, Talia Wegman-Ostrosky, Phuong L Mai, Ana F Best, Sharon A Savage

2021The Lancet Oncology119 citationsDOIOpen Access PDF

Topics & Concepts

MedicineEpidemiologyObservational studyCohort studyGermlineCancerOncologyInternal medicineEpidemiology of cancerCohortCancer registryMEDLINERetrospective cohort studyIncidence (geometry)Young adultGermline mutationDiseaseCancer incidenceCancer geneticsCancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancerBRCA gene mutations in cancer
Cancer incidence, patterns, and genotype–phenotype associations in individuals with pathogenic or likely pathogenic germline TP53 variants: an observational cohort study | Litcius