Reduction of Taylor–Aris dispersion by lateral mixing for chromatographic applications
Eiko Y. Westerbeek, Johan G. Bomer, Wouter Olthuis, Jan C. T. Eijkel, Wim De Malsche
Abstract
by a factor of three in a 40 μm × 20 μm microchannel, corresponding to a plate height gain of 2 to 3 under unretained conditions at low to high Pe values. We also demonstrate an improvement of a reverse-phase chromatographic separation of coumarins.
Topics & Concepts
Taylor dispersionMicrochannelDispersion (optics)Mixing (physics)ChromatographyReduction (mathematics)Taylor seriesChemistryMaterials scienceNanotechnologyOpticsPhysicsThermodynamicsMathematicsDiffusionGeometryQuantum mechanicsMathematical analysisMicrofluidic and Capillary Electrophoresis ApplicationsAnalytical Chemistry and ChromatographySpectroscopy Techniques in Biomedical and Chemical Research