Transcription factor competition at the γ-globin promoters controls hemoglobin switching
Nan Liu, Shuqian Xu, Qiuming Yao, Qian Zhu, Kai Yan, Jonathan Y. Hsu, Phraew Sakon, Luca Pinello, Guo‐Cheng Yuan, Daniel E. Bauer, Stuart H. Orkin
Topics & Concepts
BiologyGlobinRepressorPromoterPsychological repressionMolecular biologyLocus control regionActivator (genetics)Fetal hemoglobinTranscription factorDerepressionRegulation of gene expressionGeneticsGeneGene expressionFetusPregnancyHemoglobinopathies and Related DisordersCRISPR and Genetic EngineeringRNA modifications and cancer