Lacticaseibacillus paracasei NCU-04 relieves constipation and the depressive-like behaviors induced by loperamide in mice through the microbiome-gut-brain axis
Shengjie Li, Yi Li, Yujie Cai, Zizhou Yan, Jing Wei, Hongyan Zhang, Fenfang Yue, Tingtao Chen
Abstract
NCU-04 may offer a promising approach for treating constipation and its related depressive symptoms, supporting its potential as a functional food or adjuvant therapy for human health.
Topics & Concepts
LoperamideLactobacillus paracaseiGut microbiomeConstipationGut–brain axisMicrobiomeMedicinePsychologyNeuroscienceInternal medicineBiologyBioinformaticsLactobacillusBiochemistryDiarrheaFermentationGut microbiota and healthGastrointestinal motility and disordersProbiotics and Fermented Foods