The antidepressant-like effects of the water extract of Panax ginseng and Polygala tenuifolia are mediated via the BDNF-TrkB signaling pathway and neurogenesis in the hippocampus
Ning Jiang, Haixia Wang, Chenchen Li, Guirong Zeng, Jingwei Lv, Qiong Wang, Yin Chen, Xinmin Liu
Topics & Concepts
Behavioural despair testTail suspension testNeurogenesisTropomyosin receptor kinase BGinsengPharmacologyHippocampal formationNeurotrophic factorsHippocampusNeuroprotectionAntidepressantBrain-derived neurotrophic factorFluoxetineMedicineEndocrinologyInternal medicineBiologyNeuroscienceReceptorSerotoninPathologyAlternative medicineNeurogenesis and neuroplasticity mechanismsTryptophan and brain disordersGinseng Biological Effects and Applications