Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics
Simon Zenke, Margriet M. Palm, Julia Braun, Alina Gavrilov, Philippa Meiser, Jan P. Böttcher, Niklas Beyersdorf, Stephan Ehl, Audrey Gérard, Tim Lämmermann, Ton N. Schumacher, Joost B. Beltman, Jan Rohr
Topics & Concepts
Robustness (evolution)BiologyQuorum sensingPopulationPositive feedbackCell biologyReceptorComputational biologyImmunologyGeneticsGeneVirulenceEngineeringSociologyElectrical engineeringDemographyT-cell and B-cell ImmunologyImmune Cell Function and InteractionReceptor Mechanisms and Signaling