Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas
Mohamed Elshaer, Ahmed Islam ElManawy, Ahmed Hammad, Akhileshwar Namani, Xiu Jun Wang, Xiuwen Tang
Abstract
mutations may provide a better understanding of the molecular mechanisms associated with the progression of lung cancer and may help to provide better therapeutic approaches.
Topics & Concepts
DNA methylationBiologyMethylationEpigenomicsGeneEpigeneticsGeneticsCancer researchLung cancerAdenocarcinomaCancerGene expressionMedicinePathologyGenomics, phytochemicals, and oxidative stressEpigenetics and DNA MethylationGlutathione Transferases and Polymorphisms