Solvent-promoted photochemical carbonylation of benzylic C–H bonds under iron catalysis
Rui Qi, Tianwen Bai, Shuwang Tang, Ming Hou, Zhide Zhang, Wenlin Xie, Yangling Deng, Hongwei Zhou, Guanyinsheng Qiu
Abstract
This paper describes the iron-catalyzed photochemical carbonylation of benzylic C–H bonds resulting in the synthesis of various aryl ketones. Using 5 W blue LED irradiation, the reactions proceed smoothly in the presence of 2 mol% of FeBr 3 in MeOH at 35 °C.
Topics & Concepts
CarbonylationChemistryCatalysisPhotochemistrySolventOrganic chemistryCarbon monoxideRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsFluorine in Organic Chemistry