Nrf2/HO-1 blocks TXNIP/NLRP3 interaction via elimination of ROS in oxygen-glucose deprivation-induced neuronal necroptosis
Zhihan Liu, Ping Cheng, Tao Feng, Zhiyuan Xie, Meifang Yang, Zhiren Chen, Shuqun Hu, Dong Han, Weiwei Chen, Weiwei Chen
Topics & Concepts
NecroptosisTXNIPReactive oxygen speciesChemistryThioredoxin-Interacting ProteinCell biologyOxygenNeuroscienceBiochemistryBiologyOxidative stressProgrammed cell deathApoptosisOrganic chemistryThioredoxinHeme Oxygenase-1 and Carbon MonoxideAutophagy in Disease and TherapyInflammasome and immune disorders