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Polyhydroxyalkanoates: the natural biopolyester for future medical innovations

Zi-Wei Ren, Zeyu Wang, Yanwen Ding, Jin‐Wei Dao, Hao-Ru Li, Xue Ma, Xinyu Yang, Ziqi Zhou, Jiaxuan Liu, Chen‐Hui Mi, Zhe-Chen Gao, Pei Hua, Dai‐Xu Wei

2023Biomaterials Science37 citationsDOI

Abstract

novel synthetic biology tools. Moreover, we also systematically summarize various medical devices based on PHAs and related design approaches for medical applications, including tissue repair and drug delivery. The main degradation product of PHAs, 3-hydroxybutyrate (3HB), is recognized as a new functional molecule for cancer therapy and immune regulation. Although PHAs still account for only a small percentage of medical polymers, up-and-coming novel medical PHA devices will enter the clinical translation stage in the next few years.

Topics & Concepts

PolyhydroxyalkanoatesBusinessComputer scienceBiologyGeneticsBacteriabiodegradable polymer synthesis and propertiesElectrospun Nanofibers in Biomedical ApplicationsCarbon dioxide utilization in catalysis
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