Mucus-penetrating dendritic mesoporous silica nanoparticle loading drug nanocrystal clusters to enhance permeation and intestinal absorption
Weicheng Zhou, Biao Li, Rongting Min, Zengzhu Zhang, G. Steve Huang, Yingchong Chen, Baode Shen, Qin Zheng, Pengfei Yue
Abstract
anti-inflammatory efficacy of AG. In summary, mPEG-DMSN offers an interesting strategy to overcome the mucus clearance and epithelium barriers of the gastrointestinal tract.
Topics & Concepts
MucusMesoporous silicaNanocarriersNanoparticleParacellular transportMesoporous materialChemistryPermeationNanotechnologyAbsorption (acoustics)BiophysicsMaterials sciencePermeability (electromagnetism)Organic chemistryMembraneBiochemistryComposite materialBiologyEcologyCatalysisAdvanced Drug Delivery SystemsDrug Solubulity and Delivery SystemsAndrographolide Research and Applications