Blocking IL-17A prevents oxycodone-induced depression-like effects and elevation of IL-6 levels in the ventral tegmental area and reduces oxycodone-derived physical dependence in rats
Saadet Inan, Joseph J. Meissler, Shingo Bessho, Sonita Wiah, Çağla Tükel, Toby K. Eisenstein, Scott M. Rawls
Topics & Concepts
OxycodoneMedicineVentral tegmental areaChronic painPharmacologyPhysical dependenceAnesthesiaMorphineOpioidInternal medicinePsychiatryReceptorDopaminergicDopamineTryptophan and brain disordersTreatment of Major DepressionStress Responses and Cortisol