Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT3 receptors
Uriel López-Sánchez, Lachlan Munro, Lucy Kate Ladefoged, Anders Juel Pedersen, Christian Colding Brun, Signe Meisner Lyngby, Delphine Baud, Céline Juillan‐Binard, Miriam Grønlund Pedersen, Sarah C. R. Lummis, Benny Bang‐Andersen, Birgit Schiøtt, Christophe Chipot, Guy Schoehn, Jacques Neyton, François Dehez, Hugues Nury, Anders S. Kristensen
Topics & Concepts
ReceptorTransmembrane domainAntidepressant5-HT receptorSerotoninPharmacologyAgonistBiologyChemistryBiophysicsBiochemistryNeuroscienceHippocampusReceptor Mechanisms and SignalingIon channel regulation and functionNeuroendocrine regulation and behavior