DNMT inhibitor, 5-aza-2′-deoxycytidine mitigates di(2-ethylhexyl) phthalate-induced aggravation of psoriasiform inflammation in mice via reduction in global DNA methylation in dermal and peripheral compartments
Ali S. Alfardan, Ahmed Nadeem, Sheikh F Ahmad, Naif O. Al‐Harbi, Mohammad Alqinyah, Sabry M. Attia, Ahmed M El-Sherbeeny, Mohammad M Al-Harbi, Othman A. Al‐Shabanah, Khalid E. Ibrahim, Khalid Alhazzani, Ahmed Z. Alanazi
Topics & Concepts
InflammationChemistryMethyltransferaseDNA methylationMethylationPharmacologyDeoxycytidineDNA damageDNA methyltransferaseMedicineDNABiochemistryInternal medicineCancerGemcitabineGene expressionGeneEpigenetics and DNA MethylationTryptophan and brain disordersPsoriasis: Treatment and Pathogenesis