Long noncoding RNA SMUL suppresses SMURF2 production-mediated muscle atrophy via nonsense-mediated mRNA decay
Bolin Cai, Zhenhui Li, Manting Ma, Jing Zhang, Shaofen Kong, Bahareldin Ali Abdalla, Haiping Xu, Endashaw Jebessa, Xiquan Zhang, Raman Akinyanju Lawal, Qinghua Nie
Abstract
could be a novel therapeutic target for muscle atrophy.
Topics & Concepts
MyogenesisBiologyAtrophyMuscle atrophySkeletal muscleCell biologyNonsense-mediated decayPopulationTranslation (biology)Long non-coding RNAMyocyteTranscriptomeSMADMessenger RNARNAGeneticsGene expressionTransforming growth factorGeneEndocrinologyMedicineRNA splicingEnvironmental healthCancer-related molecular mechanisms researchRNA Research and SplicingMuscle Physiology and Disorders