Targeted Perturb-seq enables genome-scale genetic screens in single cells
Daniel Schraivogel, Andreas R. Gschwind, Jennifer H. Milbank, Daniel Leonce, Petra Jakob, Lukas Mathur, Jan O. Korbel, Christoph A. Merten, Lars Velten, Lars M. Steinmetz
Topics & Concepts
CRISPREnhancerComputational biologyBiologyTranscriptomeGenomeGeneCas9GeneticsGenome editingRNA-SeqGene expressionSingle-cell and spatial transcriptomicsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniques