A novel coumarin-triazole-thiophene hybrid: synthesis, characterization, ADMET prediction, molecular docking and molecular dynamics studies with a series of SARS-CoV-2 proteins
Rebaz Anwar Omer, Pelin Koparır, Kamuran Saraç, Metin Koparır, Damir A. Safin
Topics & Concepts
ChemistryDocking (animal)Thio-Molecular dynamicsThiopheneCoumarinCombinatorial chemistryStereochemistryCarbon-13 NMRMolecular modelComputational chemistryOrganic chemistryMedicineNursingSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsClick Chemistry and Applications