Multifunctional calcium polyphenol networks reverse the hostile microenvironment of trauma for preventing postoperative peritoneal adhesions
Pei Zhang, Yan Gong, Qingqing Pan, Zhenlin Fan, Genke Li, Mengyu Pei, Junhe Zhang, Tianyun Wang, Guangdong Zhou, Xiansong Wang, Wenjie Ren
Abstract
. The results showed that CaPNs significantly reduced inflammation, oxidative stress, fibrosis, and abdominal adhesion formation and had good hemostatic and antibacterial properties. Our findings suggest a novel strategy for the prevention of postoperative adhesions.
Topics & Concepts
MedicineAdhesionOxidative stressTissue AdhesionGallic acidInflammationIn vivoAntioxidantAbdominal surgerySurgeryPharmacologyInternal medicineBiochemistryChemistryBiologyBiotechnologyOrganic chemistryIntestinal and Peritoneal AdhesionsHernia repair and managementSurgical Sutures and Adhesives