Open questions on the transfer of chirality
Jolene P. Reid
Abstract
The transfer of chiral information from optically pure reaction components to products can generate enantiomerically-enriched molecules, but the control of stereochemistry often proves challenging. Here, the author highlights how our fundamental understanding of stereocontrol has evolved and discusses possible approaches for the rational development of enantioselective catalysts.
Topics & Concepts
Enantioselective synthesisChirality (physics)Rational designDevelopment (topology)CatalysisChemistryCombinatorial chemistryNanotechnologyStereochemistryComputer scienceMaterials scienceOrganic chemistryPhysicsMathematicsQuantum mechanicsMathematical analysisQuarkChiral symmetry breakingNambu–Jona-Lasinio modelAsymmetric Synthesis and CatalysisMolecular spectroscopy and chiralitySurface Chemistry and Catalysis