Identification of novel 4-substituted 7H-pyrrolo[2,3-d]pyrimidine derivatives as new FtsZ inhibitors: Bioactivity evaluation and computational simulation
Ting Li, Ya Zhou, Xichun Fu, Linli Yang, Hongwu Liu, Xiang Zhou, Liwei Liu, Zhibing Wu, Song Yang, Zhibing Wu, Song Yang
Topics & Concepts
FtsZGTPaseChemistryXanthomonas oryzaeLead compoundEC50Antibacterial activityBiochemistryStereochemistryBiophysicsCombinatorial chemistryIn vitroBacteriaCell divisionBiologyCellGeneticsGeneAntibiotic Resistance in BacteriaBacteriophages and microbial interactionsBacterial Genetics and Biotechnology