Electrospray-based synthesis of fluorescent poly(<scp>d</scp>,<scp>l</scp>-lactide-<i>co</i>-glycolide) nanoparticles for the efficient delivery of an anticancer drug and self-monitoring its effect in drug-resistant breast cancer cells
Manosree Chatterjee, Ritwik Maity, Souvik Das, Nibedita Mahata, Biswarup Basu, Nripen Chanda
Abstract
A novel approach used to synthesize antimetabolite-conjugated and intense blue fluorescence-emitting smart polymeric nanoparticles is reported for the efficient delivery of anticancer drugs and self-monitoring their effect in drug-resistant metastatic breast cancer cells.
Topics & Concepts
FluorescenceNanoparticleConjugated systemDrug deliveryChemistryElectrosprayLactideCombinatorial chemistryDrugNanotechnologyMass spectrometryMaterials scienceChromatographyPharmacologyOrganic chemistryMedicinePolymerQuantum mechanicsPhysicsPolymerizationMass Spectrometry Techniques and ApplicationsAdvanced biosensing and bioanalysis techniquesElectrohydrodynamics and Fluid Dynamics