Gut microbiota influence in type 2 diabetes mellitus (T2DM)
Andrew Cunningham, Jeffrey W. Stephens, Dean Harris
Abstract
A strong and expanding evidence base supports the influence of gut microbiota in human metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is clearly associated with the development of type 2 diabetes mellitus (T2DM) and associated complications. Understanding the causal association between gut microbiota and metabolic risk has the potential role of identifying susceptible individuals to allow early targeted intervention.
Topics & Concepts
Gut floraType 2 Diabetes MellitusDiabetes mellitusGlucose homeostasisMedicineMedical microbiologyType 2 diabetesBioinformaticsImmunologyBiologyPhysiologyEndocrinologyInsulin resistanceGut microbiota and healthDiet and metabolism studiesClostridium difficile and Clostridium perfringens research