Litcius/Paper detail

anndata: Access and store annotated datamatrices

Isaac Virshup, Sergei Rybakov, Fabian J. Theis, Philipp Angerer, F. Alexander Wolf

2024The Journal of Open Source Software196 citationsDOIOpen Access PDF

Abstract

anndata is a Python package for handling annotated data matrices in memory and on disk (github.com/scverse/anndata),positioned between pandas and xarray.anndata offers generic data access features including, among others, sparse data support, lazy operations, and a PyTorch interface. Statement of needGenerating insight from high-dimensional data matrices typically works through training models that annotate observations and variables via low-dimensional representations.In exploratory data analysis, this involves iterative training and analysis using original and learned annotations and task-associated representations.anndata offers a canonical data structure for book-keeping these, which is neither addressed by pandas (McKinney, 2010), nor xarray (Hoyer & Hamman, 2017), nor commonly-used modeling packages like scikit-learn (Pedregosa et al., 2011).

Topics & Concepts

Computer scienceR packageComputational biologyBiologyProgramming languageSingle-cell and spatial transcriptomicsHydrology and Watershed Management StudiesPrecipitation Measurement and Analysis