Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy
Wei Wu, Qiuping Zhou, Takeya Masubuchi, Xiaoshan Shi, Hua Li, Xinyi Xu, Min Huang, Meng Li, Xing He, Hengyu Zhu, Shuaixin Gao, Nan Zhang, Ruirui Jing, Jie Sun, Haopeng Wang, Enfu Hui, Catherine Chiulan Wong, Chenqi Xu
Topics & Concepts
Immunoreceptor tyrosine-based activation motifT-cell receptorCD3BiologyCell biologySignal transductionChimeric antigen receptorJurkat cellsPhosphorylationT cellTyrosine kinaseProtein kinase domainAntigenSH2 domainBiochemistryImmunologyCD8Immune systemGeneMutantCAR-T cell therapy researchViral Infectious Diseases and Gene Expression in InsectsSilicon Carbide Semiconductor Technologies