Water extract of goji berries improves neuroinflammation induced by a high-fat and high-fructose diet based on the bile acid-mediated gut–brain axis pathway
Wei Dong, Yujie Huang, Yifan Shu, Xia Fan, Xinyi Tian, Yamei Yan, Jia Mi, Lu Lu, Xiaoxiong Zeng, Youlong Cao
Abstract
, known as a potentially beneficial bacterium. These results demonstrated that LBE could ameliorate neuroinflammation and cognitive impairment in HFFD-induced mice through the gut-liver-brain axis, which might be due to the regulation of BA homeostasis and gut microbiota in mice.
Topics & Concepts
NeuroinflammationFructoseBile acidGut–brain axisChemistryFood scienceBiochemistryBiologyGut floraInflammationImmunologyDiet and metabolism studiesDiet, Metabolism, and DiseaseBiochemical effects in animals