Halogen bonding organocatalysis enhanced through intramolecular hydrogen bonds
Asia Marie S. Riel, Daniel A. Decato, Jiyu Sun, Orion B. Berryman
Abstract
Recent results indicate a halogen bond donor is strengthened through direct interaction with a hydrogen bond to the electron-rich belt of the halogen. Here, this Hydrogen Bond enhanced Halogen Bond (HBeXB) plays a clear role in a catalyst. Our HBeXB catalyst improves product conversion in a halide abstraction reaction over a traditional halogen bonding derivative.
Topics & Concepts
Halogen bondHalogenChemistryIntramolecular forceHydrogen bondCatalysisOrganocatalysisPhotochemistryHalideHydrogen atom abstractionDerivative (finance)Polymer chemistryCombinatorial chemistryHydrogenOrganic chemistryMoleculeEnantioselective synthesisEconomicsFinancial economicsAlkylCrystallography and molecular interactionsFluorine in Organic ChemistryAsymmetric Synthesis and Catalysis