Chiral separation of five antihistamine drug enantiomers and enantioselective pharmacokinetic study of carbinoxamine in rat plasma by HPLC-MS/MS
Meng Li, Junyuan Zhang, Siman Ma, Zhen Jiang, Xin Di, Xingjie Guo
Abstract
Chiral separation and pharmacokinetic study of antihistamine drugs.
Topics & Concepts
ChemistryAntihistamineEnantiomerPharmacokineticsChromatographyEnantioselective synthesisHigh-performance liquid chromatographyDrugPharmacologyStereochemistryOrganic chemistryCatalysisMedicineAnalytical Chemistry and ChromatographyAntibiotics Pharmacokinetics and EfficacyAnalytical Methods in Pharmaceuticals