Peptide-assisted Intracellular Delivery of Biomacromolecules
Shiroh Futaki, Jan Vincent V. Arafiles, H. Hirose
Abstract
Intracellular delivery of biomacromolecules offers opportunities for molecular and materials design, based on an understanding of their chemical properties and their modes of cellular responses. Peptides are advantageous as a delivery tool because of their ease in functional design and synthesis. This review highlights our approaches for the intracellular delivery of biomacromolecules using peptides with distinct modes of action.
Topics & Concepts
ChemistryIntracellularPeptideBiochemistryRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesSilk-based biomaterials and applications