Zwitterionic silver nanoparticle based antibacterial eye drops for efficient therapy of bacterial keratitis
Yangjing Bai, Li Ma, Ying-Chun Huang, Shiying Lang, Wenjie Fan, Gongyan Liu
Abstract
BK rabbit models showed that the ZP@Ag-drops effectively inhibited corneal infection and prevented ocular tissue damage, surpassing the therapeutic effect of commercial levofloxacin eye drops (LEV-drops). Overall, this study presents a promising alternative option for the effective treatment of BK using antibacterial eye drops.
Topics & Concepts
Antibacterial activityChemistryIn vivoKeratitisBiocompatibilityCorneaSilver nanoparticleMicrobiologyNanoparticleBacteriaNanotechnologyMaterials scienceMedicineBiologyOrganic chemistryOphthalmologyGeneticsBiotechnologyOcular Infections and TreatmentsOcular Surface and Contact LensCorneal Surgery and Treatments