MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?
Jehuda Soleman, Rina Dvir, Liat Ben‐Sira, Michal Yalon, Frederick A. Boop, Shlomi Constantini, Jonathan Roth
Abstract
Traditional management of newly diagnosed pediatric brain tumors (PBTs) consists of cranial imaging, typically magnetic resonance imaging (MRI), and is frequently followed by tissue diagnosis, through either surgical biopsy or tumor resection. Therapy regimes are typically dependent on histological diagnosis. To date, many treatment regimens are based on molecular biology. The scope of this article is to discuss the role of diagnosis and further treatment of PBTs based solely on MRI features, in light of the latest treatment protocols. Typical MRI findings and indications for surgical biopsy of these lesions are described.
Topics & Concepts
MedicineMagnetic resonance imagingRadiologyBiopsyGlioma Diagnosis and TreatmentNeuroblastoma Research and TreatmentsNeurofibromatosis and Schwannoma Cases