A simple method for the synthesis of <i>N</i>-difluoromethylated pyridines and 4-pyridones/quinolones by using BrCF<sub>2</sub>COOEt as the difluoromethylation reagent
Albert Gandioso, Mohamed El Fakiri, Anna Rovira, Vicente Marchán
Abstract
A simple transition-metal free method was developed for the synthesis of <italic>N</italic>-difluoromethylated pyridinium-containing compounds and 4-pyridones/quinolones.
Topics & Concepts
ReagentSimple (philosophy)ChemistryCombinatorial chemistryOrganic chemistryPhilosophyEpistemologyFluorine in Organic ChemistrySynthesis and Reactions of Organic CompoundsInorganic Fluorides and Related Compounds