MicroRNA-320a-containing exosomes from human umbilical cord mesenchymal stem cells curtail proliferation and metastasis in lung cancer by binding to SOX4
Huan Xie, Jie Wang
Abstract
the SOX4/Wnt/β-catenin axis, which highpoints the potency of exosomes expressing miR-320a as a possible therapeutic option for lung cancer treatment.
Topics & Concepts
MicrovesiclesMesenchymal stem cellCancer researchWnt signaling pathwayMetastasismicroRNALung cancerCancer stem cellBiologyCancerImmunologyStem cellMedicineCell biologySignal transductionPathologyInternal medicineGeneBiochemistryExtracellular vesicles in diseaseMicroRNA in disease regulationCircular RNAs in diseases