Downregulation of microRNA-155-5p prevents immune thrombocytopenia by promoting macrophage M2 polarization via the SOCS1-dependent PD1/PDL1 pathway
Yu‐Ying Chang, Xi Chen, Yaoyao Tian, Xinyu Gao, Zhiyu Liu, Xiushuai Dong, Lianjie Wang, Fei He, Jin Zhou
Topics & Concepts
Suppressor of cytokine signaling 1Gene silencingMacrophage polarizationmicroRNADownregulation and upregulationImmunologyImmune systemTransfectionPeripheral blood mononuclear cellPlateletCancer researchMedicineMacrophageBiologyGeneIn vitroGeneticsSuppressorPlatelet Disorders and TreatmentsImmune cells in cancerMyeloproliferative Neoplasms: Diagnosis and Treatment