Cell-cell contact-induced gene editing/activation in mammalian cells using a synNotch-CRISPR/Cas9 system
Hongxin Huang, Xin Zhang, Jie Lv, Hongcheng Yang, Xinlong Wang, Shufeng Ma, Ruoyang Shao, Xin Peng, Ying Lin, Zhili Rong
Topics & Concepts
CRISPRGenome editingBiologyGeneHuman geneticsCellStem cellGeneticsCas9Cell biologyComputational biologyCRISPR and Genetic EngineeringVirus-based gene therapy researchCAR-T cell therapy research