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Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces

Atul Deshpande, Melanie Loth, Dimitrios N. Sidiropoulos, Shuming Zhang, Long Yuan, Alexander T.F. Bell, Qingfeng Zhu, Won Jin Ho, Cesar A. Santa‐Maria, Daniele M. Gilkes, Stephen R. Williams, Cedric R. Uytingco, Jennifer Chew, Andrej Hartnett, Zachary Bent, Alexander V. Favorov, Aleksander S. Popel, Mark Yarchoan, Ashley Kiemen, Pei‐Hsun Wu, Kohei Fujikura, Denis Wirtz, Laura D. Wood, Lei Zheng, Elizabeth M. Jaffee, Robert A. Anders, Ludmila Danilova, Genevieve Stein-O’Brien, Luciane T. Kagohara, Elana J. Fertig

2023Cell Systems40 citationsDOIOpen Access PDF

Topics & Concepts

Tumor microenvironmentContext (archaeology)BiologyComputational biologyTranscriptomeImmunotherapySpatial analysisImmune systemGeneGene expressionImmunologyGeneticsGeographyPaleontologyRemote sensingSingle-cell and spatial transcriptomicsImmune cells in cancerT-cell and B-cell Immunology
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces | Litcius