The epitranscriptional factor PCIF1 orchestrates CD8+ T cell ferroptosis and activation to control antitumor immunity
Bolin Xiang, Meiling Zhang, Kai Li, Zijian Zhang, Yutong Liu, Minling Gao, Xiyong Wang, Xiangling Xiao, Yishuang Sun, Chuan He, Jie Shi, Hongzeng Fan, Xixin Xing, Gaoshan Xu, Yingmeng Yao, Gang Chen, Haichuan Zhu, Chengqi Yi, Jinfang Zhang
Topics & Concepts
Cytotoxic T cellCD8T cellBiologyChimeric antigen receptorImmunotherapyCancer researchCancer immunotherapyImmunologyAntigenImmune systemBiochemistryIn vitroRNA modifications and cancerCancer-related molecular mechanisms researchCancer-related gene regulation