Interleukin-2 immunotherapy reveals human regulatory T cell subsets with distinct functional and tissue-homing characteristics
Miro E. Raeber, Dominic Caspar, Yves Zurbuchen, Nannan Guo, Jonas Schmid, Jan Michler, A Martin, Urs C. Steiner, Andreas E. Moor, Frits Koning, Onur Boyman
Abstract
Treg cells. Collectively, these data define the distinct human Treg cell subsets that are responsive to IL-2 immunotherapy.
Topics & Concepts
Homing (biology)ImmunologyImmune systemImmunotherapyBiologyCD38T cellHumanized mouseCancer researchCell biologyStem cellCD34EcologyT-cell and B-cell ImmunologyImmune Cell Function and InteractionSystemic Lupus Erythematosus Research