Ribociclib mitigates cisplatin-associated kidney injury through retinoblastoma-1 dependent mechanisms
JY Kim, Laura A. Jayne, Yuntao Bai, Mei Ji He Ho Feng, Matthew A. Clark, Sangwoon Chung, John W. Christman, Rachel E. Cianciolo, Navjotsingh Pabla
Topics & Concepts
Retinoblastoma proteinCisplatinCancer researchCell cycleDNA damageCell cycle checkpointRetinoblastomaAcute kidney injuryCancerCyclin-dependent kinaseCarcinogenesisCyclin-dependent kinase 1NephrotoxicityGene silencingKinaseMedicinePharmacologyKidneyBiologyCell biologyInternal medicineChemotherapyGeneGeneticsBiochemistryDNAAdvanced Breast Cancer TherapiesCancer-related Molecular PathwaysNeuroendocrine Tumor Research Advances