MiR-7 deficiency promotes Th1 polarization of CD4+T cells and enhances the antitumor effect in adoptive cell therapy for lung cancer
Xian Chang, Juanjuan Zhao, Ya Zhou, Mengmeng Guo, Yaping Yan, Ya Wang, Xu Zhao, Jing Yang, Chao Chen, Lin Tang, Ming Qin, Lin Xu
Topics & Concepts
CD8T cellCancer researchCytotoxic T cellCD28Adoptive cell transferChemistryMolecular biologyInterleukin 21Flow cytometryImmunologyBiologyImmune systemIn vitroBiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses