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NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

Auvro R. Mridha, Alexander Wree, Avril A. B. Robertson, Matthew M. Yeh, Casey D. Johnson, Derrick M. Van Rooyen, Fahrettin Haczeyni, Narci Teoh, Christopher Savard, George N. Ioannou, Seth L. Masters, Kate Schroder, Matthew A. Cooper, Ariel E. Feldstein, Geoffrey C. Farrell

2017Journal of Hepatology1,073 citationsDOIOpen Access PDF

Topics & Concepts

InflammasomeSteatohepatitisFibrosisInflammationFatty liverLiver injuryMedicineEndocrinologyCholesterolInternal medicineImmunologyChemistryDiseaseLiver Disease Diagnosis and TreatmentInflammasome and immune disordersLiver physiology and pathology
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice | Litcius