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Dexmedetomidine suppresses bupivacaine-induced parthanatos in human SH-SY5Y cells via the miR-7-5p/PARP1 axis-mediated ROS

Ting Zheng, Chunying Zheng, Fei Gao, Fengyi Huang, Bin Hu, Xiaochun Zheng

2020Naunyn-Schmiedeberg s Archives of Pharmacology18 citationsDOI

Topics & Concepts

SH-SY5YDexmedetomidineCell biologyBupivacainePARP1IntracellularViability assayBiologyPharmacologyBiochemistryApoptosisCell cultureNeuroblastomaPoly ADP ribose polymeraseGeneticsGeneSedationPolymerasePARP inhibition in cancer therapyCardiac Ischemia and ReperfusionMicroRNA in disease regulation
Dexmedetomidine suppresses bupivacaine-induced parthanatos in human SH-SY5Y cells via the miR-7-5p/PARP1 axis-mediated ROS | Litcius