Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer
Cristina Muntean, Eva Blondeel, L. Harinck, Kunal Pednekar, Jai Prakash, Olivier De Wever, Jeanne Leblond Chain, Stefaan C. De Smedt, Katrien Remaut, Koen Raemdonck
Topics & Concepts
Small interfering RNAGene silencingEndocytosisChemistryEndosomePharmacologyGene knockdownTransfectionIntracellularCell biologyBiochemistryCellBiologyApoptosisGeneRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesImmunotherapy and Immune Responses