Iodine-125 seed implantation in the treatment of malignant tumors
Pan Hu, Jianwen Huang, Yanling Zhang, Huanqing Guo, Guanyu Chen, Fujun Zhang
Abstract
Malignant tumors are major causes of morbidity and mortality in China. Despite advances in surgical, radiological, chemotherapeutic, molecular targeting, and immunotherapeutic treatments, patients with malignant tumors still have poor prognoses. Low-dose-rate brachytherapy, specifically 125I seed implantation, is beneficial because of its high local delivery dose and minimal damage to surrounding tissues. Consequently, it has gained increasing acceptance as a treatment modality for various malignant tumors. In this study, we explored the fundamental principles, clinical applications, and new technologies associated with 125I radioactive seed implantation.
Topics & Concepts
BrachytherapyMedicineRadiological weaponDose rateIodineRadioactive iodineRadiologyOncologyRadiation therapyInternal medicineMedical physicsChemistryThyroidOrganic chemistryAdvanced Radiotherapy TechniquesRadiation Therapy and DosimetryMedical Imaging Techniques and Applications