Interim Report of a Japanese Phase II Trial for Cardiac Stereotactic Body Radiotherapy in Refractory Ventricular Tachycardia ― Focus on Target Determination ―
Mari Amino, S. Kabuki, Etsuo Kunieda, Jun Hashimoto, Akitomo Sugawara, T. Sakai, Susumu Sakama, Kengo Ayabe, Yohei Ohno, Atsuhiko Yagishita, Yoshinori Kobayashi, Yuji Ikari, Koichiro Yoshioka
Abstract
Background: Cardiac radiotherapy using stereotactic body radiation therapy (SBRT) has attracted attention as a minimally invasive treatment for refractory ventricular tachycardia. However, a standardized protocol and software program for determining the irradiation target have not been established. Here, we report the first preclinical stereotactic radioregulation antiarrhythmic therapy trial in Japan, focused on the target-setting process.
Topics & Concepts
MedicineVentricular tachycardiaCardiac electrophysiologyRadiologyMagnetic resonance imagingRadiation therapyRadiosurgeryInternal medicineRefractory (planetary science)Clinical trialCardiologyElectrophysiologyAstrobiologyPhysicsCardiac Arrhythmias and TreatmentsCardiac electrophysiology and arrhythmiasCardiac pacing and defibrillation studies