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ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation

Rui Sun, Zibo Meng, Hye-Yoon Lee, Rienk Offringa, Christof Niehrs

2023Cell chemical biology40 citationsDOIOpen Access PDF

Topics & Concepts

Degradation (telecommunications)Leverage (statistics)Protein degradationBusinessComputer scienceCell biologyBiologyTelecommunicationsArtificial intelligenceProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisUbiquitin and proteasome pathways
ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation | Litcius