SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition
Taha Azad, Ragunath Singaravelu, Emily E.F. Fekete, Zaid Taha, Reza Rezaei, Rozanne Arulanandam, Stephen Boulton, Jean‐Simon Diallo, Carolina S. Ilkow, John C. Bell
Topics & Concepts
BiosensorEctodomainLuciferaseProtein-fragment complementation assayViral entryChemistrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyDirected evolutionVirusComputational biologyBiochemistryBiophysicsComplementationCoronavirus disease 2019 (COVID-19)BiologyReceptorViral replicationTransfectionMedicineGeneInfectious disease (medical specialty)PathologyDiseaseMutantPhenotypebioluminescence and chemiluminescence researchAdvanced biosensing and bioanalysis techniquesSARS-CoV-2 detection and testing