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STING-induced regulatory B cells compromise NK function in cancer immunity

Sirui Li, Bhalchandra Mirlekar, Brandon M. Johnson, W. June Brickey, John A. Wrobel, Na Yang, Dingka Song, Sarah Entwistle, Xianming Tan, Meng Deng, Ya Cui, Wei Li, Benjamin G. Vincent, Michael Gale, Yuliya Pylayeva‐Gupta, Jenny P.‐Y. Ting

2022Nature317 citationsDOIOpen Access PDF

Topics & Concepts

StingStimulator of interferon genesCancer researchBiologyInnate immune systemInterferonImmune systemImmunologyPancreatic cancerIRF3ImmunosuppressionCancerAerospace engineeringGeneticsEngineeringinterferon and immune responsesImmune Cell Function and InteractionImmune cells in cancer
STING-induced regulatory B cells compromise NK function in cancer immunity | Litcius