Unlocking the Chain‐Walking Process in Gold Catalysis**
Vivek W. Bhoyare, Akash G. Tathe, Vincent Gandon, Nitin T. Patil
Abstract
The successful realization of gold-catalyzed chain-walking reactions, facilitated by ligand-enabled Au(I)/Au(III) redox catalysis, has been reported for the first time. This breakthrough has led to the development of gold-catalyzed annulation reaction of alkenes with iodoarenes by leveraging the interplay of chain-walking and π-activation reactivity mode. The reaction mechanism has been elucidated through comprehensive experimental and computational studies.
Topics & Concepts
CatalysisReactivity (psychology)ChemistryRedoxChain reactionChain (unit)Ligand (biochemistry)Combinatorial chemistryAnnulationReaction mechanismNanotechnologyPhotochemistryOrganic chemistryMaterials sciencePhysicsReceptorPathologyAstronomyMedicineBiochemistryAlternative medicineCatalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and Catalysis