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Pre‐symptomatic transmission of novel coronavirus in community settings

Dechuan Kong, Zheng Yang, Huanyu Wu, Hào Pān, Abram L. Wagner, Yaxu Zheng, Xiaohuan Gong, Yiyi Zhu, Bihong Jin, Wenjia Xiao, Shenghua Mao, Sheng Lin, Ruobing Han, Xiao Yu, Peng Cui, Chenyan Jiang, Qiwen Fang, Yihan Lu, Chen Fu

2020Influenza and Other Respiratory Viruses18 citationsDOIOpen Access PDF

Abstract

We used contact tracing to document how COVID-19 was transmitted across 5 generations involving 10 cases, starting with an individual who became ill on January 27. We calculated the incubation period of the cases as the interval between infection and development of symptoms. The median incubation period was 6.0 days (interquartile range, 3.5-9.5 days). The last two generations were infected in public places, 3 and 4 days prior to the onset of illness in their infectors. Both had certain underlying conditions and comorbidity. Further identification of how individuals transmit prior to being symptomatic will have important consequences.

Topics & Concepts

Interquartile rangeIncubation periodContact tracingCoronavirus disease 2019 (COVID-19)Transmission (telecommunications)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Medicine2019-20 coronavirus outbreakComorbidityCoronavirusIncubationDemographyInternal medicineVirologyBiologyDiseaseOutbreakInfectious disease (medical specialty)Computer scienceTelecommunicationsSociologyBiochemistryCOVID-19 epidemiological studiesCOVID-19 Digital Contact TracingData-Driven Disease Surveillance
Pre‐symptomatic transmission of novel coronavirus in community settings | Litcius