Anticholinesterase activities of novel indole-based hydrazide-hydrazone derivatives: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction
Ebru Didem Coşar, Efe Doğukan Dincel, Sedanur Demiray, Ece Sucularlı, Ezgi Tüccaroğlu, Nurten Özsoy, Nuray Ulusoy‐Güzeldemirci
Topics & Concepts
ChemistryProtein Data Bank (RCSB PDB)In silicoADMEHydrazideHydrazoneDocking (animal)StereochemistryAcetylcholinesteraseAchéIndole testProton NMRCarbon-13 NMREnzymeIn vitroCombinatorial chemistryBiochemistryOrganic chemistryGeneMedicineNursingCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsMedicinal Plants and Neuroprotection